cyfra

http://www.fdi.com/documents/products/sheets/Cyfra%2021-1%20EIA%20July%202009%20(2).pdf

Cyfra 21-1 adalah cytokeratin 19 fragmen yang ditemukan dalam serum dari pasien kanker. Precise recognition of this fragment is made with two monoclonal antibodies (BM 19-21 and KS 19-1)* which were obtained after immunisation of mice with MCF-7 cells. Tepat pengakuan fragmen ini dibuat dengan dua monoklonal antibodi (BM 19-21 dan KS 19-1) * yang diperoleh setelah imunisasi tikus dengan sel-sel MCF-7. Cytokeratin 19 (CK19) is a member of the intermediate filament group of proteins, whose physiological role remains unclear. Cytokeratin 19 (CK19) adalah anggota kelompok filamen intermediat protein, peran fisiologis yang masih belum jelas.
It is an acid-type cytoplasmic protein, with a molecular weight of 40 000 D, expressed in simple epithelium. Ini adalah jenis asam sitoplasma protein, dengan berat molekul 40 000 D, dinyatakan dalam epitel sederhana. On the death of the cell, it is released into the serum in the form of soluble fragments. Pada kematian sel, itu dilepaskan ke dalam serum dalam bentuk fragmen larut. In immunohistochemistry, CK19 is found in the cytoplasm of the epithelial tumor cell, including that of bronchial cancers. Dalam imunohistokimia, CK19 ditemukan dalam sitoplasma dari sel tumor epitel, termasuk kanker bronkial.
Preliminary clinical studies of bronchial cancer patients sera have shown that CYFRA 21-1 assay is useful in the diagnosis and follow-up of non-small cell lung carcinoma and particularly of squamous cell carcinoma of the lung. Studi klinis awal pasien kanker bronkial sera telah menunjukkan bahwa assay 21-1 Cyfra berguna dalam diagnosis dan tindak lanjut non-sel kecil dan karsinoma paru terutama karsinoma sel skuamosa paru-paru.

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lengkap, translate

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lengkap

http://www.ria-cis.com/ressources/produits/02_GB_ELSACYFRA_Mod21.pdf

baru

http://chestjournal.chestpubs.org/content/109/4/995.full.pdf

http://lib.bioinfo.pl/meid:106848

http://pharm.shams.edu.eg/Postgraduates/continuing_education/3.pdf

http://www.imbiomed.com.mx/1/1/articulos.php?method=showDetail&id_articulo=24192&id_seccion=1666&id_ejemplar=2484&id_revista=25